The Genome Miners

What is bioinformatics?

" Bioinformatics is software used for analyzing genome sequences, studying proteins and genes, cataloguing and searching genomic databases, and managing biological information.

It is used in medical research, the study of bioterrorism agents and other life science applications "

[Michael Hardy on: Federal Computer Week 17 (17), 38 - 39 (2003)

The Human Genome Project has piled up a mountain of data.

Computer-aided pattern recognition will help pharmaceutical companies to identify key-disease-causing genes

REFERENCES

Computational Structural Biology at http://cbcg.lbl.gov/ssi-csb/index.html

"Pattern Discovery in Biomolecular Data" by Jason.T.L. Wang, Bruce. A.Shapiro, Dennis Shasha (eds.), Oxford Univ. Press (1999). The book's homepage is <http://www.cis.njit.edu/~jason/publications/biopat.html> . This page provides links to biological pattern discovery tools and some major biological database centers around the world.

To access the bioinformatics databases maintained by the National Center for Biotechnology Information (NCBI), go to http://www.ncbi.nlm.nih.gov

Human / Mouse Homology Relationships at http://www.ncbi.nml.nih.gov/Homology/ (a list of useful links is reported.

The bioinformatics market covers the 5% of the total biotech market (the 2004 biotech market is approx. 27 billion dollars; the 2006 biotech market should be 40 billion dollars)t

BioInform, a newsletter on the subject of bioinformatics, can be accessed at http://www.bioinform.com

The Genome Miners

Selected companies

I J

The Genome Miners
	COMPANY	LOCATION	WEB SITE
B	Bioreason	Santa Fe', NM, U.S.A.	www.bioreason.com
	Biosift (ex eBioinformatics, ex Entigen)	Cambridge, MA, U.S.A.	www.biosift.com

C	Celera Genomics	Rockville, MD, U.S.A.	www.celera.com
	Cengent Therapeutics (ex Structural Bioinformatics)	San Diego, Ca, U.S.A. Broendby, Denmark	www.strubix.com
	Compugen	Tel Aviv, Israel Jamesburg, NJ, U.S.A.	www.compugen.co.il www.cgen.com
	CuraGen Corp.	New Haven, CT, U.S.A.	www.curagen.com
	Cybergenetics	Pittsburgh, PA, U.S.A.	www.cybgen.com

D	Decodon	Greifswald, Germany	www.decodon.com

E	Exelixis (ex Genomica)	South San Francisco, CA, U.S.A.	www.exelixis.com

F	First Genetic Trust	Lyndhurst, NJ, U.S.A.	www.firstgenetic.net

G	Gemini Holdings	UK	www.gemini-research.co.uk
	Genomatics	Munich, Germany	www.genomatix.de
	GPC AG	Martinsried, Germany	www.gpc-ag.com

H	Hyseq, Inc.	Sunnyvale, CA, U.S.A.	www.hyseq.com

I	IBM	Armonk, NY, U.S.A.	www.research.ibm.com
	Incyte Genomics	Palo Alto, CA, U.S.A.	www.incyte.com
	Infogen	Berlin, Germany
	InforMax (sold to Invitrogen)	Bethesda, MD, U.S.A.	www.informaxinc.com

L	Lion Bioscience (alliance with Infogen)	Heidelberg, Germany	www.lionbioscience.com www.lion-ag.de

N	Neomorphic (sold to Affimetrix)	Berkeley, CA, U.S.A.	www.neomorphic.com
	NetGenics(sold to Lion Biosciences)	Cleveland, OH, U.S.A.	www.netgenics.com

O	Oxford Molecular Group	Oxford, UK	www.oxmol.co.uk

P	Paracel	Pasadena, CA, U.S.A.	www.paracel.com
	Partek	St. Charles, Missouri, U.S.A.	www.partek.com
	PHASE-1 Molecular Toxicology, Inc.	Santa Fe, NM, U.S.A.	www.phase1tox.com

S	Sequenom	San Diego, CA, U.S.A. - Hamburg, Germany	www.sequenom.com
	Silicon Genetics	San Carlos, CA, U.S.A.	www.sigenetics.com
	Silicon Graphics	Mountain View, CA, U.S.A.	www.sgi.com
	SpotFire	Somerville, MA, U.S.A.	www.spotfire.com
	Synomics	Cambridge Business Park, UK	www.synomics.com

T	TimeLogic	Crystal Bay, NV, U.S.A.	www.timelogic.com