The Montegen's Pocket-Science

 

Content of Volume 5 (2001)

 

January

"Gene silencing" in transgenic plants

February

The use of 2D polyacrylamide gel electrophoresis (PAGE) for the identification of specific proteins

Pharmacogenomics: Another Evolution - The promise of exploiting genomic diversity is still at its infancy.

"Creare una azienda su Internet"

Digital Signatures

Bioterrorism and Biodefense

March

Introduction to the tool "Design Structure Matrix (DSM)".

April

Obit

Vincenzo Montecucchi, General, The Carabinieri Corps (by Pier Carlo Montecucchi)

April 17, Carmagnola (Turin, Italy)

« Old soldiers never die, they just fade away »

93^ Sezione Mista Carabinieri - Vicende Storiche

June

Biometric security systems and personal privacy

A survey on the collaboration between Industry and University in Italy

September

September 11 terroristic attack in New York, Washington and Pennsylvania

 We wish to express our sincerest condolences to all those affected by the horrible events

 

"At the going down of the

sun and in the morning

we will remember them."

(from "For The Fallen" - by Laurence Binyon, 1914)

 

October

Biodetectors: some considerations on biometrics

November

Science with ethics: the role of the patients in the genetics revolution

December

Post-traumatic stress disorder (PTSD)

 

 

Barra 

 

 

 

January

"Gene silencing" in transgenic plants

This is a phenomenon where the expression of an inserted foreign gene becomes unintentionally suppressed. Nevertheless scientific data indicate that an inserted foreign gene may switch off an endogenous gene (endogenous gene = a gene which was already in the plant before the genetic modification was introduced). This phenomenon has been reported also in animals (Drosophila).

References:

"A similarity between viral defense and gene silencing in plants"  by F. Ratcliff, B.D. Harrison, D.C. Baulcombe (1997) Science 276, 1558 - 1560 (specific references on gene silencing are reported in the paper)

"A species of small antisense RNA in posttranscriptional gene silencing in plants" by A.J. Hamilton and D.C. Baulcombe (1999) Science 286, 950-952

"Political Compliance V Sound Science - Biotech Debacle Set to Unfold Further?" - "This posting looks at some important findings by the John Innes Centre [(JIC) a UK research institute funded by both government and industry-backed sponsors] on biosafety and other issues in relation to GM crops, and examines their significance in the context of the current political climate influencing the relationship between industry and bio-science.

 

 

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February

The use of 2D polyacrylamide gel electrophoresis (PAGE) for the identification of specific proteins

Reference:

"Proteomic analysis of Epstein-Bar virus-transformed human B-lymphoblastiod cell lines before and after immortalization" by T. Toda, M. Sugimoto, A. Omori, T. Matsuzaki, Y. Furuichi, N. Kimura (2000)1998) Electrophoresis 21 (9), 1814 - 1822

"Molecular Mechanisms of Ageing (Internet World Congress 98) - Proteome database for aging research"

TMIG (Tokyo Metropolitan Institute of Gerontology) - 2D PAGE : Age-related Proteome Database    the data are available at the following web page: http://proteome.tmig.or.jp/2D/Fibro/table_window.html

 

Pharmacogenomics: Another Evolution

by Julia Boguslavsky (2001), Drug Discovery & Development (January) 40 - 42

 

Creare una azienda su Internet: business virtuale ma reale

by Pier Carlo Montecucchi (2001), La Stampa (Febbraio 12) - Sezione Ebusiness di Luca De Biase  ("Le vostre esperienze nella imprenditoria online")

 

Digital Signatures

 

Bioterrorism and Biodefense

An open discussion starting from the article: "The Nightmare of Bioterrorism" by Laurie Garrett (2001), Foreign Affairs, January / February, 76 - 89 and from the book "Vector" by Robin Cook, (1999), G.P. Putnam's Sons, New York

 

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March

Introduction to the tool "Design Structure Matrix (DSM)".

"The Design Structure Matrix (DSM) differs from conventional project-management tools in that it focuses on representing information flows rather than work flow. Thus, it is better able to depict the key dynamic of innovation processes." (from: "Innovation at the Speed of Information" by Steven D. Eppinger (2001), Harvard Business Review, January, 149 - 158.

Details on the technology are available on the Internet at the URL address: http://web.mit.edu/dsm 

 

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April

Obit by Pier Carlo Montecucchi

Montecucchi 

Vincenzo Montecucchi, General, the Carabinieri Corps, received many honors during his life time, including threee War Cross for Military Valour  (World War II, period 1940 - 1943), one  Gold Cross of Merit and one Gold Medal for Merit ,  two honourable mentions, a particular mention from the R. Government of Albania (World War II, 1940),  a Mention in Dispatches (Legione Territoriale Carabinieri, Torino, October 2, 1964), the title of "Cavaliere dell'Ordine al Merito della Repubblica Italiana", the title of "Ufficiale dell'Ordine al Merito della Repubblica Italiana", the title of "Console Militare del Touring Club Italiano". He was prisoner in Germany (1944). He offered  a great contribution during the period of Resistenza in Cuneo and in  its  suburbs. He died April 17, 2001, in Carmagnola (Italy).

My father  has been an excellent and unique spiritual and physical teacher for me and I like to report here the same words used by G. Hamel in a dedication to his father:

" There is no one who has taught me more.

There is no one I hold in higher regard.

It is my greatest fortune to be his son."

 

93^ Sezione Mista Carabinieri - Vicende Storiche [notizie ottenute dal Comando Generale dell'Arma dei Carabinieri - Ufficio Storico (Si ringrazia in particolare il Col. Vincenzo Pezzolet)]

93^ Sezione Mista Carabinieri

 Vicende Storiche

Centro di mobilitazione

Legione Carabinieri di Catanzaro - Posta alle dipendenze della Divisione di Fanteria "Taro"

Data di costituzione

10 giugno 1940

Data partenza da Catanzaro per Civitavecchia

13 giugno 1940

Data rientro al centro (smobilitata)

19 agosto 1940

Data ricostruzione della Sezione

22 settembre 1940

Data partenza da Catanzaro per Bari

26 novembre 1940

Data imbarco da Bari per l'Albania

30 Novembre 1940 - Piroiscafo "Puccini"

Data sbarco a Durazzo

1^ dicembre 1940

Forza organica iniziale

  • 1 Tenebnte - Comandante di Sezione
  • 1 Maresciallo Capo - vicecomandante
  • 4 Vicebrigadieri, di cui un contabile ed un motociclista
  • 2 Appuntati, di cui un ciclista
  • 40 Carabinieri, di cui 4 motociclisti, 2 autisti e 12 ciclisti

La Sezione venne sciolta il 19 agosto e ricostruita il 22 settembre dello stesso anno (1940) con una forza organica di 7 sottufficiali e 58 militari di truppa.

Fatti d'arme importanti cui la 93^ Sezione prese parte

I militari della 93^ Sezione disimpegnarono servizi di polizia militare al seguito della Divisione di Fanteria "Taro", operante, inizialmente, sul fronte greco-albanese e successivamente in Francia, dove la Sezione si disgrego' in conseguenza degli eventi bellici dell'8 settembre 1943.

Dislocazione del reparto alla data dell'8 settembre 1943

Bormes (Francia)

Data scioglimento Sezione

8 settembre 1943

Perdite subilte per cause di servizio di guerra

Negativo

Perdite subite a causa degli eventi bellici dell'8 settembre 1943

  • Morti: 1 Carabiniere
  • Feriti: negativo
  • Dispersi: 1 Sottufficiale, 1 Carabiniere, 1 Carabiniere Ausiliario

Militari recuperati

  • Ufficiali: n. 1
  • Sottufficiali: n. 3
  • Appuntati: n. 2
  • Carabinieri: n. 46

Varie

Il Tenente Vincenzo Montecucchi ha comnandato la 93^ Sezione dal 10 giugno al 19 agosto 1940 e dal 24 aprile 1941 al 27 marzo 1943, data, quest'ultima, sotto la quale venne trasferito alla Compagnia di Cuneo, in seguito a promozione a Capitano

 

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June

Biometric security systems and personal privacy

The available technologies (including: fingerprint readers, retinal scanners, facial- recognition cameras, voice-recognition) are discussed with reference to the recent paper "Bio-Keys" by Sally Wiener Grotta (2001), PC Magazine (June 12, pages 162 - 174).

See the table "Biometropolis" in the section "Security and Intrusion 2000"

At present, the combination of "bio-keys" with smart cards and passwords represent the best solution for personal identification., with the respect of the individual privacy.

 

A survey on the collaboration between Industry and University in Italy

A discussion has been organized about the situation on the collaboration between Industry and University in Italy starting from the document: "Working together, creating knowledge: the university - industry research collaborative initiative". This report was published June 11, by the Business - Higher Education Forum (American Council on Education) and it is available on the 'net at the web page http://www.acenet.edu

The comments published at this regard on the magazine Nature (411, 723 and  728, 2001) have been taken into consideration.

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October

Biodetectors: Some considerations on biometrics ("Biometropolis" on Security and Intrusion 2002 )

A biometric is a measurement of a biological characteristic. Biometrics represent forms of authentication

"Biometric security systems grant—or deny—access to buildings, information and benefits by automatically verifying the identity of people through their distinctive physical or behavioral traits (from: MSNB: "5 ways to make America safer" - October 28 at www.msnb.com ). Once "captured," a biometric is translated algorithmically into a complex string of numbers and stored in a database as a template. Later, this template can be compared to any "live" biometric presented as proof of identity."

Biometric systems::

  • Finger imaging
  • Hand geometry
  • Facial recognition
  • Voice authetication
  • Iris scanning: customer's eye  => iris pattern => iris code (the iris-scanning security technology appears to have some problems if referred to people affected by glaucoma and under treatment with prostaglandin analogues)
  • Retinal scanning

Other biometric systems:

  • Body odor
  • Ear shape
  • Gait recognition
  • Facial thermography
  • Signature verification
  • Vein check

Biometric systems are employed for two main purposes:

 identification ( = "who is this person ") : the identity of a subject is determined by comparing a measured biometric against a dastabase of stored records; a one-to-many comparison of an individual's submitted biometric sample against the entire database of biometric reference templates to determine whether it matches any of the templates and, if so, the identity of the enrollee whose template was matched. The one-to-many approach is seeking to find an identity within a database, rather than verify a claimed identity;

verification ( = "is this person who he claims to be?") : the verification compares a measured biometric with one known to come from a particular person; it is a comparison of two sets of biometrics to determine  if they are from the same individual; it is a one-to-one comparison of a live finger and a previously enrolled record to ensure that the applicant is who he / she claims to be.

Different biometrics are used for different kinds of security check

Amsterdam Airport (E.U.) installs Eye-Scanny Security System

Logan International Airport (Boston, MA, U.S.A.) is using Facial Recognition

(from: The International Herald Tribune (The IHT ONLINE at www.iht.com)

Facial recognition will be used soon in Arizona, California, Coloradou

References:

"Iris recognition" by John Daugman in: American Scientist , July - August 2001; John Daugman's Web page at www.cl.cam.ac.uk/users/jgd1000/

"Watching you" on: The Economist,  September 22nd, 2001, 63 - 64

"Eye security"  by S. Longstaff on:  The Economist (Letters) , October 6th, 2001 (page 22) (iris recognition, glaucoma, prostaglandin analogues)

"Biometrics explained" on the Internet at the URL address: www.iosoftware.com/biometrics/ of the compani I/O Software, Inc. (CA, U.S.A.)

INSPass (Immigration Naturalization Services Passenger accelerated service system) at: http://www.biometrics.org/REPORTS/INSPASS.html ; http://www.biometrics.org/REPORTS/INSPASS2.html ; http://www.panynj.gov/aviation/inspassmain.htm  

"Gattaca" (http://www.gattaca.com), a science fiction triller; a world of the future has been created on the basis of the genetic testing"

See the table "Biometropolis" in the section "Security and Intrusion 2000"

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November

 Science with ethics: the role of patients in the genetic revolution - Considerations on the article: " Who owns my disease" by Arthur Allen, on Mother Jones (http://motherjones.com) , November - December, 2001, pages 52 - 57, 88 - 89. The mentioned disease is called pseudoxantoma elasticum (PXE, for short).  On this topic please visit the web page of Genetic Alliance at http://www.geneticalliance.org

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December

Post-traumatic stress disorder (PTSD) - called also "post-traumatic stress syndrome" (or "shell shock" or "battle fatigue") was first recognized during World War I. Tratment can be individual tailored ("The Last Coyote" by Michael Connelly, 1995).

Mental Health Information

Organization

URL

American Association of Suicidology

www.suicidology.org

American Psychiatric Association

www.psych.org

American Psychological Association

www.apa.org

Centers for Disease Control and Prevention

www.cdc.gov/ndipc

Healing Depression

www.celexa.com

National Alliance for the Mantally Ill (NAMI)

www.nami.org

National Depressive and Manic-Depressive Associationc

www.ndmda.org

National Mental Health Associations

www.nmha.org

National Institute of Mental Health

www.nimh.nih.gov

World Fellowship for Schizophrenia and Allied Disorders

www.world-schizophrenia.org

Reference: Wendy Huntington - The New York Times Magazine, page 41, October 28, 2001 (modified)

 

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